Results 1. The device realizes automatic loading, automatic photo capture and coordinates, automatic sample point (robot coordinate error + -0.1MM), 23 channels with separate pipelines, which can control one channel individually or all at the same time, and perform CCD during the sample process. Monitor camera (this process needs to be tested). It has error reporting and error correction functions. Take photos after clicking to make sure the products are uniform. (And save photos) make up for individual points in case of missing points. When a defective product appears, the device displays the defective product group number, and the marking is done manually (the function of marking defective products can also be added, and a coordinate station needs to be added)

2. All materials used in the instrument meet GMP requirements. Easy to clean, maintain, and produce no dust. The container used for loading samples should be able to achieve cleaning and sterilization.

Ranch

3. Other requirements: prevent cross-contamination:

a. The simultaneous sampling of multiple channels should strictly control cross-contamination that cannot occur between each channel. The 21 channels are completely independent, and reagents are completely separated during loading.

4. Membrane fixing: Because the material of the membrane strip is soft, the negative pressure method should be used, and the spot should be avoided.

Workflow The operator places the entire film in the equipment workbench. The manipulator automatically sucks one sheet. During the adsorption process, an ion wind blows the film to prevent the phenomenon of sucking two or more sheets. After the manipulator positions the film strip, the device automatically generates a negative pressure and adsorbs the film strip. The device CCD system Film line for coordinate recognition,

After recognizing the coordinates, the equipment moves the station. (The rotation uses the servo system for positioning.) The equipment moves the spotting robot to the spotting robot according to the coordinates. The CCD monitors the spotting process (if feasible). After the spotting is completed, check whether there are any missing points and whether the spots are out of the grid. When the missing point is still out of the grid state, the device monitoring interface will display the coordinates and position. When missing or missing points occur, the manipulator makes up points based on the coordinates, and the device will remind you of the spotting status after the spotting is finished. After the sample is finished, the negative pressure of the equipment will be released, and the robot will take out the product after the sample is finished. Personnel mark defective films. (Or machine mark)

When not in use for a long time (such as 20-30 minutes), the device will automatically pump back the unspotted liquid in the tube to the bottle.